Oral Maxillofac Surg Clin North Am v.b20, n.b02, May 2008

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Annual malignant transformation rate is 3% and most strongly predicted by presence of dysplasia on biopsy; increasing duration, increasing size and nonhomogenous appearance also associated with malignant transformation. Definition / general. White, confluent patches of fluffy (hairy) mucosa, bilateral, along lateral tongue. Associated with HIV+ patients (AIDS may appear within 2 - 3 years) but actually due to EBV infection. Balloon cells with margination of chromatin (nuclear beading); EBV present in clear cells of spinous layer. Non-homogenous leukoplakia has a greater risk of malignancy than homogenous. Location matters - floor of mouth and ventral tongue lesions higher risk for malignancy.

Leukoplakia tongue pathology outlines

Vocal Cord Polyp Pathology Outlines . Leukoplakia Pathology Outlines . Precancerous Leukoplakia On Vocal Cords . Vocal Cord Leukoplakia Icd 10 10 specimens taken from oral hairy leukoplakia were compared to 8 histological preparations from hairy tongue.

Rosin FC(1), Barcessat AR(2), Borges GG(1), Ferreira LG(1), Corrêa L(3).

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Pyogenic granuloma - not classically a tongue lesion. Granular cell tumour - classically base of tongue, may be malignant. Malignant. Squamous cell carcinoma.

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Definition / general. White, confluent patches of fluffy (hairy) mucosa, bilateral, along lateral tongue. Associated with HIV+ patients (AIDS may appear within 2 - 3 years) but actually due to EBV infection. Balloon cells with margination of chromatin (nuclear beading); EBV present in clear cells of spinous layer. Non-homogenous leukoplakia has a greater risk of malignancy than homogenous. Location matters - floor of mouth and ventral tongue lesions higher risk for malignancy. Gross.

Oral leukoplakia is an oral potentially malignant disorder (OPMD) that presents as white patches of the oral mucosa. According to the World Health Organization, the term leukoplakia should be reserved for "white plaques of questionable risk, having excluded other known diseases or disorders that carry no increased risk for cancer" [].A separate disorder that is not premalignant 2013-06-14 2019-08-05 10 specimens taken from oral hairy leukoplakia were compared to 8 histological preparations from hairy tongue. We found 9 criteria helpful concerning the histopathologic differential diagnosis of these entities. Oral hairy leukoplakia shows a gently papillated surface, a prominent horny layer with c … Nonhomogeneous leukoplakia on tongue/floor of mouth had a 43.10-fold higher risk compared to homogeneous lesions located on buccal mucosa or other sites (P < .05). However, homogeneous leukoplakia in buccal mucosa or other sites of the oral cavity still had the possibility of having carcinoma within the lesion. This report describes a rare case of glycogenic acanthosis (GA) located on the tongue of a 72-year-old man.
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Oral hairy leukoplakia is caused by Epstein-Barr virus (EBV) infection of the oral mucosa. It most often occurs in association with HIV infection. It has been less frequently described in immunosuppressed patients, especially following organ transplantation, and is rare in immune competent individuals. Histology of oral hairy leukoplakia Non-homogenous leukoplakia has a greater risk of malignancy than homogenous.

Microscopic. Features: Often associated with epithelial thickening (hyperkeratosis, acanthosis). DDx: Food debris. Infectious: aphthous ulcers candidiasis (thrush) hairy leukoplakia herpes simplex virus infectious mononucleosis verruca vulgaris Inflammatory (noninfectious): geographic tongue glossitis granulomatous inflammation inflammatory fibrous hyperplasia (pending) inflammatory papillary hyperplasia Melkersson-Rosenthal syndrome peripheral giant cell granuloma tongue ulceration with eosinophilia Leukoplakia or "white patch": represents benign hyperkeratosis in 80% of cases, dysplasias in 12%, carcinoma in situ (CIS) in 3%, and invasive carcinomas in 5% of cases Erythroplakia or "red patch": is a particularly ominous oral mucosal lesion, representing carcinoma in 51% of cases, severe dysplasia or CIS in 40% of cases, and mild to moderate dysplasia in 9% of cases The patients with histologically confirmed leukoplakia are reported to have no malignant transformation in 86.6% after 3 years of follow-up and 82.0% after 5 years.
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ICD-10: K13.21 - Leukoplakia of oral mucosa, including tongue. Epidemiology.

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Features: Often associated with epithelial thickening (hyperkeratosis, acanthosis). DDx: Food debris. In oral hairy leukoplakia, the mucosa displays mild papillary acanthosis (figure 1). Hyperkeratosis and marked parakeratosis of the superficial epithelial layer is a prominent feature (figure 2).